Improving muscle weakness
As we get older, our muscles get weaker. For some of us, this starts to cause problems, such as falling, or finding it more difficult to get around and do things in our daily lives. In addition, it can take us longer to recover from even minor illnesses when our muscles are weak.
This muscle weakness is very common, and we are committed to finding ways to keep older people strong and healthy.
This clinical trial will investigate whether a medicine used for the heart (perindopril) and a food supplement (leucine) can help your muscles become stronger, and so improve what you are able to do. The study design will mean that you will either take the study medicine and supplement or a placebo (dummy.)
Participation in the trial is entirely voluntary and you may withdraw at any time.
What is involved?
For the study you will be asked to attend your local hospital 6 to 8 times over a year. Each visit will take approximately one to two hours. Taxi transport can be arranged or travel expenses reimbursed.
At each visit you will be seen by a Research Nurse. During these visits the nurse will do a simple health check and assess your balance, walking and muscle strength. The nurse will go through some questionnaires about how you have been feeling. You will also have some blood samples taken. At the start and end of the trial we will perform a scan of your muscles and bones.
As part of the trial you will be asked to take a study tablet once a day, and sprinkle a small scoop of the food supplement in your food or drink three times a day.
By taking part you are contributing to medical science and the results may help other people in the future.
Will taking Part in the study be kept confidential
All your details will remain strictly confidential and will be stored in keeping with the Data Protection Act 1998.
If you are interested in taking part in this study or would like any more information please contact the study team in your area.